Clomid, as does Nolvadex, works by occupying the binding sites of estrogen receptors of cells, without activating the receptors. This reduces the extent to which estradiol can activate these receptors. In the case of the hypothalamus, this leads to the hypothalamus “concluding” that estrogen levels are low. If androgen levels are not elevated, as indeed they should not be after an anabolic steroid cycle, the hypothalamus is then stimulated to produce LHRH.
See dosing guide
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